New clinical research indicates expansion of ashwagandha’s capabilities

Native to the ancient landscapes of Northern India, ashwagandha has graced traditional Ayurvedic practices for centuries, offering respite to those besieged by stress​.

The credibility of ashwagandha has been the subject of quality-related debates, questioning the very essence of what makes this plant special. In Vidya’s state-of-the-art facility in Bangalore, this botanical relic has been elevated to meet the stringent requirements of modern life and science.

Vidya enlists third-party testing facilities, to scrutinize the extracts meticulously, thereby confirming the presence of active ingredients at the percentages boldly claimed. This ensures that every capsule is not just a capsule, but a repository of verified, concentrated wellness.

Capturing the spectrum of wellness seekers​

Vidya does not merely interact with nature; it engages in a dialogue with it. The company’s newest clinically-researched ingredient, Asera™, known scientifically as Withania Somnifera​ (ashwagandha), is a perfect example of this symbiosis.

It is critical to understand the inner architecture of Asera™. It's not merely a shrub; it's a complex biological system. Within this intricacy lies two cornerstone elements: withanolides and oligosaccharides. These compounds are nature's alchemists, transforming stress into serenity, unease into equilibrium. Their combined impact on cortisol levels – a key physiological indicator of stress – is profound and rooted in scientific authenticity.

In an evolving world where wellbeing is increasingly at the forefront of consciousness, Asera™'s potential appeal is vast. Understanding the diverse segments of the population that could greatly benefit from its properties helps tailor its application and message:

• Stress-relief seekers ​The overwhelmed looking for calm

• Holistic health enthusiasts ​Natural remedy believers for body and soul

• Yoga and meditation practitioners ​Enhancing mindfulness from within

• Proactive aging individuals ​Navigating the challenges of aging naturally

• Fitness enthusiasts ​Balancing rigorous physical regimes with inner serenity

• Professionals in high-stress jobs ​For those whose roles demand constant alertness

• Students ​Easing academic pressures and future uncertainties

• Sleep-deprived individuals ​Aiding in the quest for quality rest

• Alternative medicine practitioners ​Recommending nature's solutions

• Mental wellness advocates ​Prioritizing mind wellness through nature's gifts

An art of formulation​

When contemplating the architecture of a single capsule, there was a design challenge: the limitation of space. The very vessel that holds the potency of Asera™ is constrained by its dimensions.

Yet, this limitation provided an opportunity for brilliance. Vidya initiated an in-depth clinical study to fine-tune the formulation to a laser-precise 160mg daily dose. During this process, it was discovered that beyond the acknowledged 10% withanolide standard, there lies a rich tapestry of other beneficial elements.

These 'secondary' compounds comprise 90% of the plant's essence and interact synergistically withanolides. Consequently, Vidya innovated a 30% oligosaccharide standardization, emphasizing the symbiotic and synergistic relationship between these active ingredients.

Scientific validation: A clinical journey​

The final frontier of Vidya’s inquiry was a meticulously designed, two-month-long, randomized, double-blind, parallel-group clinical trial. A cohort of healthy but stressed adults was engaged. The study was launched with dual objectives, each significant yet distinct:

• Understanding how the precise 160mg daily dose impacts cortisol levels

• Assessing its efficacy in modulating self-perceived states of stress and anxiety

The outcome unfolded like a symphony of data, each note resonating with scientific and statistical significance:

• A statistically significant reduction in anxiety was achieved, as corroborated by the DASS-21 stress questionnaire (p<0.001). From the onset to the conclusion of the study, participants reported a considerable shift towards a state of calmness

• Depression levels showed a marked improvement, with p-values less than 0.002, indicating a considerable uplift in mood

• Anxiety levels, as assessed by the Hamilton Anxiety Rating Scale (HAM-A), reduced significantly from the baseline (p<0.007)

• The pièce de résistance was the marked decline in cortisol levels, registering a p-value of less than 0.001

Vidya’s commitment to scientific authenticity initiated a methodical expedition, an extensive clinical trial designed to scrutinize the efficacy of the Asera™ formulation.

Figure 1: Effects of Asera™ on clinical endpoints.​​

The values display the mean±SD across three diverse endpoints. Through a meticulous paired t-test analysis there were compelling findings: p<0.001 for cortisol, p<0.002 for DASS-21, and p<0.007 for HAM-A versus control, when set against the baseline.

Yet, the exploration didn't end there. Vidya ventured further to compare Asera™ against a widely recognized ashwagandha brand on the market.

                                                                 ​​

 ​Figure 2: Effects Asera​™ vs. Leading Brand on clinical endpoints.​​

Once again, the values represent the mean±SD spanning three different endpoints. Paired test data analysis showcased a pivotal revelation. For endpoints (such as, self-perceived anxiety, depression levels, anxiety levels determined via HAM-A, and cortisol concentrations) Asera™ exhibited a more pronounced reduction or improvement over Leading Brand. Most notably, Asera™ was superior in terms of the total responses in the DASS-21 anxiety questionnaire. While both products displayed significant results, the greater statistical significance in cortisol levels underscored the supremacy of Asera™’s effect.

 The difference in data between Asera™ and Leading Brand:

• Cortisol: p<0.001 for Asera™ vs. p<0.013 for Leading Brand

• DASS-21: p<0.002 for Asera™ vs. p<0.006 for Leading Brand

• HAM-A: p<0.007 for Asera™ vs. p<0.001 for Leading Brand

The conclusions from this clinical process were unequivocal. A lower dose of Asera™ isn’t just viable; it is supremely therapeutic. The statistically significant results observed are not only astounding in their own right but also indicate marked superiority in certain metrics compared to established norms.

A vital differentiator for Vidya’s product in the crowded market landscape is the emphasis on high oligosaccharide standardization, setting Asera™ a class apart.

The resounding conclusions​

This data is a confirmation of Vidya’s commitment to align traditional wisdom with scientific precision. It corroborates that the 160mg Asera™ formulation doesn't just hold up to scrutiny – it thrives under it. The harmonious integration of withanolides and oligosaccharides offers a comprehensive approach to stress management, marking a paradigm shift in Vidya’s understanding of plant-based wellness.

Asera™ is more than an ancient plant; it's a masterstroke of botanical engineering, a blend of nature's finest assets refined and encapsulated for wellbeing. Vidya is more than a provider of clinically-researched ashwagandha, Asera™; it is also custodians of a legacy that spans millennia, now validated by rigorous scientific scrutiny.

In a world awash with uncertainty, Asera™ stands as a testament to what's possible when meticulous craftsmanship meets scientific rigor. It's not just a supplement; it's a finely tuned instrument for wellness, rigorously tested and definitively proven.