Urolithin A

Timeline raises CHF 56M from L’Oréal and Nestlé in Series D financing

19-Jan-2024 By Stephen Daniells

Swiss longevity biotech company Timeline (parent company Amazentis) announced that it has raised CHF 56 million (US$ 66 million) in an oversubscribed Series D financing round that included strategic investments by L’Oréal and Nestlé.

Verdure’s pomegranate extract shows potential for gut microbiome support and mitochondrial health

04-Jan-2024 By Stephen Daniells

Daily supplementation with Verdure’s punicalagin-enriched pomegranate extract may boost the relative abundance of beneficial gut microbes and increase production of short-chain fatty acids, according to a new RCT.

Study sheds light on pomegranate extract’s gut-mediated metabolism

13-Oct-2023 By Asia Sherman

A pharmacokinetics study published in the Journal of Pharmaceutical and Biomedical Analysis provides a closer look at how potent phenolic compounds in a standardized pomegranate extract are metabolized by gut microbiota to confer health benefits.

Timeline raises questions about Urolithin A supplements on Amazon

30-Aug-2023 By Stephen Daniells

Some dietary supplements on Amazon showing urolithin A on their label do not contain any of the cellular aging ingredient, alleges a new analysis by Timeline (formerly Amazentis) shared with NutraIngredients-USA.

Study supports urolithin A's potential for mitochondrial function & joint health

12-Sep-2022 By Nicola Gordon-Seymour

An investigation into the effect of urolithin A (UA) on mitophagy and mitochondrial function in knee joint cells shows supplementation improved mitochondrial health and had positive effects on joint function and mobility in both healthy and osteoarthritis...

Urolithin A & muscle strength: Science builds for compound’s healthy aging potential

31-May-2022 By Stephen Daniells

Supplementation with urolithin A, a pomegranate metabolite, may boost exercise endurance and physical performance, according to findings from a randomized clinical trial with 88 healthy people.

Urolithin A could combat age-related muscle decline, study suggests

09-Feb-2022 By Kavitha Sivasubramaniam

A placebo-controlled, randomised clinical trial has indicated that urolithin A supplementation has a positive impact on skeletal muscle performance and mitochondrial health among an older population.

Individual gut microbiome responses to pomegranate overcome by direct urolithin A supplementation

20-Jul-2021 By Stephen Daniells

Only about 40% of people may have the gut microbes to convert ellagitannins from pomegranate into urolithin A, an ingredient positioned for boosting mitochondrial and muscle function, but direct supplementation with the compound overcomes these individual...