Mitochondrial Function

Timeline raises CHF 56M from L’Oréal and Nestlé in Series D financing

19-Jan-2024 By Stephen Daniells

Swiss longevity biotech company Timeline (parent company Amazentis) announced that it has raised CHF 56 million (US$ 66 million) in an oversubscribed Series D financing round that included strategic investments by L’Oréal and Nestlé.

Q&A: StayAbove Nutrition on ‘mitocentric’ approach to combat aging and obesity

15-Jan-2024 By Asia Sherman

Canada-based startup StayAbove Nutrition is targeting rising obesity rates and age-related disorders along common pathways of cellular dysfunction with multi-ingredient supplements built and backed by science.

Verdure’s pomegranate extract shows potential for gut microbiome support and mitochondrial health

04-Jan-2024 By Stephen Daniells

Daily supplementation with Verdure’s punicalagin-enriched pomegranate extract may boost the relative abundance of beneficial gut microbes and increase production of short-chain fatty acids, according to a new RCT.

ChromaDex launches ‘clinical strength’ Tru Niagen Pro

02-Nov-2023 By Stephen Daniells

California-based ChromaDex Corp. has launched a high dose Tru Niagen product containing 1,000 mg of its Nicotinamide Riboside ingredient.

NPA’s Fabricant on NMN: ‘Taking FDA to Federal Court is expensive, but I don’t see another option’

12-Sep-2023 By Stephen Daniells

The US Food and Drug Administration (FDA) has been unable to reach a decision on the requests made in a Citizen Petition about NMN due to “competing agency priorities”, a response that threatens the NMN sector, says Daniel Fabricant, PhD.

Timeline raises questions about Urolithin A supplements on Amazon

30-Aug-2023 By Stephen Daniells

Some dietary supplements on Amazon showing urolithin A on their label do not contain any of the cellular aging ingredient, alleges a new analysis by Timeline (formerly Amazentis) shared with NutraIngredients-USA.

Nestle targets mitochondria to support healthy aging

06-Jun-2023 By Olivia Brown

Nestle health science has focussed its research and development work on the healthy aging category, predicting a “tsunami of metabolic conditions” for the future of public health.

RCT supports nicotinamide riboside boost for muscle mitochondrial biogenesis

19-Jan-2023 By Stephen Daniells

Supplementation with nicotinamide riboside may improve muscle mitochondrial biogenesis, according to data from a first-of-its kind five-month-long clinical study with twins.

Bioenergy goes deeper into mechanism of action of legacy D-Ribose ingredient

17-Jun-2022 By Hank Schultz

Bioenergy Life Sciences says new data will help expand the playing field for its legacy ribose ingredient. The new line of development centers on AMPK activation.

Olive compound may boost mitochondrial function, support liver health

03-Jun-2022 By Stephen Daniells

Hydroxytyrosol from olives may reverse the negative effects of a high fat diet on both mitochondrial function and liver health, suggests new data from a study using seabass.

Urolithin A & muscle strength: Science builds for compound’s healthy aging potential

31-May-2022 By Stephen Daniells

Supplementation with urolithin A, a pomegranate metabolite, may boost exercise endurance and physical performance, according to findings from a randomized clinical trial with 88 healthy people.

Urolithin A could combat age-related muscle decline, study suggests

09-Feb-2022 By Kavitha Sivasubramaniam

A placebo-controlled, randomised clinical trial has indicated that urolithin A supplementation has a positive impact on skeletal muscle performance and mitochondrial health among an older population.

Spermidine may protect against age-related heart mitochondrial changes

13-Jan-2022 By Stephen Daniells

Supplementing the diet with spermidine may protect the mitochondria in hearts of older individuals, suggests data from a mouse study from Austria & Germany.

Higher-uptake CoQ10 form boosts cycling performance

23-Aug-2021 By Hank Schultz

Supplementing with a special form of CoQ10 boosted performance in a cycling time trial, a recent study has found.

New research will place D-ribose atop ‘mitochondrial health’ pyramid, expert says

17-Aug-2021 By Hank Schultz

Thirty years after the launch of Bioenergy Ribose, the ingredient’s manufacturer says new research is expanding the view of its effects in the cell. This could lead to a new ‘mitochondrial health’ category, with D-ribose as one of the key players, a...

Individual gut microbiome responses to pomegranate overcome by direct urolithin A supplementation

20-Jul-2021 By Stephen Daniells

Only about 40% of people may have the gut microbes to convert ellagitannins from pomegranate into urolithin A, an ingredient positioned for boosting mitochondrial and muscle function, but direct supplementation with the compound overcomes these individual...