Probiotic combination may boost skin and sleep for women: Pilot study

Eight weeks of supplementation with Lalleland’s Cerebiome probiotic blend led to significant improvements in skin firmness, elasticity, and hydration, as well better sleep
“This psychobiotic not only supports gut and mental well-being, but also significantly enhances skin health, offering a holistic approach to beauty and wellness," said Elodie Aragon, product manager at Lallemand Health Solutions (Getty Images)

Eight weeks of supplementation with Lalleland’s Cerebiome probiotic blend led to significant improvements in skin firmness, elasticity and hydration, as well better sleep, says a new study.

Data published in the International Journal of Probiotics and Prebiotics indicated that the combination of Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 was also associated with improvements in stress, according to the PSS-10 subjective stress questionnaire.

The study was performed by scientists from Lallemand’s Rosell Institute for Microbiome and Probiotics using their probiotic combination that is positioned for the gut-brain axis. The combination is supported by 10 clinical studies on stress and mental well-being plus multiple preclinical studies that reportedly show eight distinct mechanisms of action on the microbiome-gut-brain axis.

“We are thrilled to share these findings of our latest study on Cerebiome,” said Elodie Aragon, product manager at Lallemand Health Solutions. “This psychobiotic not only supports gut and mental well-being but also significantly enhances skin health, offering a holistic approach to beauty and wellness.

“There is a big potential for the nutricosmetics brands, as the market is valued at $8.09 billion in 2023 and projected to reach $11.91 billion by 2028, growing at a compound annual growth rate of 8%,” she added.

Study details

The new open-label, single-arm, proof-of-concept study included 35 healthy women aged between 30 and 45. All the women received 3 billion CFU of Cerebiome per day for eight weeks. There was no placebo/control group.

Results showed that the probiotic was associated with significant increases in skin hydration of the face and body of 21% and 18%, respectively, after eight weeks.

Skin firmness was also found to have increased by 12% after eight weeks of Cerebiome supplementation, the researchers said. Reductions in the appearance of wrinkles and fine lines were also reported with, for example, a 21% decrease in the appearance of forehead wrinkles reported at the end of the study.

Over 80% of the women also stated that their skin felt smoother and had an improved texture.

The probiotic was also reported to improve measures of stress, with a 31% reduction in perceived stress reported by the women after eight weeks, as measured by the PSS-10 questionnaire.

“These results confirm previous effects of the tested formulation Cerebiome on perceived stress,” wrote the researchers, led by Dr. Sylvie Binda, vice president of research & development at Lallemand Health Solutions.

Dr. Binda and her co-workers also reported significant improvements in sleep quality among the participants, with enhancements in their ability to fall asleep and stay asleep.

“This study offers valuable evidence supporting the holistic approach of using probiotics to ameliorate perceptions of stress and skin quality, potentially through the gut–brain–skin axis," they concluded. “It opens the doors for future research, encouraging further exploration and validation of the role of probiotics and gut microbiomes on skin quality parameters in larger, more diverse populations.”


Source: International Journal of Probiotics and Prebiotics, 20(1), 1–9. doi : 10.37290/ijpp2641-7197.20:1-9. " A subjective evaluation of the effects of a probiotic formulation on skin quality in young adult females: Open-label proof-of-concept study”. Authors: O. Kassem, et al.