Bioavailability

LEO-HB bioavailability-boosting tech expands options for challenging ingredients

19-Dec-2023 By Stephen Daniells

Working with some ingredients is difficult because of their low dispersion or low bioavailability, but the LEO-HB technology can boost both and expand opportunities for formulators in the food, beverage, and supplements space.

Specnova’s Sebastian Balcombe on advances in liposomal technology

10-Nov-2023 By Claudia Adrien

Liposomes are delivery vehicles for transporting substances into the body, and they are Sebastian Balcombe’s forte. Balcombe, founder and CEO of biotechnology company Specnova, spoke with NutraIngredients-USA at this year’s SupplySide West about the advances...

NutraCast: Less is more: The evolution of high bioavailable natural products

20-Oct-2023 By Danielle Masterson

Since 2003, SourceOne has provided health and wellness solutions to brands around the world. Its focus is on clinically-proven formulations combined with technologically-advanced and patented delivery systems. Jesse Lopez, CEO and Founder of SourceOne...

AI for enhanced bioavailability: “there’s no other way” says expert

05-Oct-2023 By Olivia Brown

Experts have discussed the importance of using AI to create ingredients with enhanced nutrient bioavailability, yet highlight the significant cost and time implications as key challenges for researchers and product developers.

Particle size matters: Taiyo on SunActive Fe’s absorption pathway

28-Aug-2023 By Asia Sherman

Ingredient supplier Taiyo International is spotlighting findings from a recent study comparing the heightened bioavailability of its SunActive Fe ingredient to other iron fortifiers on the market.

Study explores pharmacokinetics of liposomal and non-liposomal multivitamins

10-Aug-2023 By Asia Sherman

Ingesting a liposomal multivitamin and mineral supplement (MVM) distinctively affects the appearance and/or clearance of vitamins and minerals in the blood compared to a non-liposomal MVM supplement, according to a recent study.

Liquid-liquid encapsulation innovation offers simple, low-cost opportunities for nutraceuticals

31-Jul-2023 By Stephen Daniells

An innovative more affordable liquid-liquid encapsulation system may offer multilayer encapsulation in milliseconds and expand production opportunities for new products by encapsulating multiple core materials in the same parcel.

AstraGin amplifies arginine absorption and boosts nitric oxide production, study shows

13-Jul-2023 By Asia Sherman

NuLiv Science is positioning its ingredient AstraGin as a game-changer for pre-workout effectiveness and cardiovascular health based on the findings of a new study.

RCT shows joint health support with OmniActive’s Curcuwin Ultra+

26-Jun-2023 By Stephen Daniells

Supplementation with a highly bioavailable curcumin formulation may improve knee joint health and mobility in people with mild osteoarthritis, says a new multi-centric, randomized, double-blind, parallel, placebo-controlled study.

NutraCast: Making ingredients into ‘superstars’ via liposomal delivery system

26-May-2023 By Danielle Masterson

Specnova is tapping pharmaceutical technology to improve bioavailability, taste and has a shelf life.

Meta-analyses support curcumin’s weight management potential

18-Apr-2023

The list of benefits associated with curcumin supplements may extend to weight management, says a new review of meta-analyses.

Enriched postbiotic calcium may boost mineral bioavailability: RCT

07-Apr-2023

Calcium enriched in a Lactobacillus-based postbiotic system is associated with higher levels of bioavailability as compared to calcium citrate, while a calcium-enriched yeast-based postbiotic does not influence calcium absorption, according to a new study...

Calanus oil matches krill and fish oil for Omega-3 Index boosts: Study

30-Mar-2023 By Stephen Daniells

Calanus oil may be equally as effective at increasing the Omega-3 Index as fish oil and krill oil, says a new study that supports the copepod-derived oil as an alternative marine omega-3 source.

Ingredient Optimized partners with Nutrabound Labs to offer plasma-blasted collagen

05-Dec-2022 By Asia Sherman

New York biotech company Ingredient Optimized is partnering with Texas-based manufacturer Nutrabound Labs to offer finished products using the recently-launched ioCollagen protein technology.

Diverse polyphenol-rich ingredient may provide ‘sustained exposure’ to bioactives

28-Nov-2022 By Stephen Daniells

A combination of polyphenol rich extracts from multiple botanicals may boost levels of beneficial metabolites in the blood and help fill gaps associated with low fruit and vegetable consumption, says a new study from Fytexia.

Pectin improves quercetin bioavailability, according to researchers

04-Nov-2022 By Nicola Gordon-Seymour

Scientists have developed a method to bind quercetin derivatives to pectin chains to enhance bioavailability and antioxidant activity for improved disease prevention.

Canadian contract manufacturer debuts new melt delivery technology

01-Nov-2022 By Hank Schultz

A new melt delivery option has debuted in North American markets, the developer announced this week.

‘A rare phenomenon’: Experts weigh in on DILIN data linking turmeric supplements to liver injury

24-Oct-2022 By Stephen Daniells

A new paper reports a small number of cases of liver injury associated with turmeric supplements, but independent experts tell us that any such phenomena appear to be “rare”, and noted that the botanical has a low risk profile.

NextEvo launches Revive CBD Complex Curcumin and Hemp Extract

28-Sep-2022 By Asia Sherman

NextEvo Naturals has added Revive CBD Complex Curcumin and Hemp Extract to its line of water-soluble CBD products, formulated and clinically proven to maximize absorption.

Study supports bioavailability boost for liposomal Ginkgo extract

15-Sep-2022 By Stephen Daniells

The liposomal Ginkgo ingredient Ginkgosome may increase absorption of key ginkgolide compounds by about 2-fold, compared to a regular, commercial Ginkgo extract, says a new study from Australia.

VitamINSIGHTS – Delivery system innovation

‘Now is the time’: Moderna co-founder and nutra experts on why delivery system innovation is key for industry growth

31-May-2022 By Tingmin Koe

Breakthrough in delivery system technologies is crucial to drive innovation in the traditional vitamin and minerals category, as well as the booming probiotics, functional food and beverage sectors.

"The possibilities are endless:" New technology converts bioactive oils into water-soluble powders

04-Apr-2022 By Danielle Masterson

Prodalim debuted the new platform at Expo West, demonstrating how innovation continues to push the intersection between nutrition and technology forward.

OmniActive’s new curcumin shows 144x bioavailability at low doses vs standard curcumin: Study

23-Mar-2022 By Stephen Daniells

OmniActive Health Technologies’ new Curcuwin Ultra+ ingredient, launched last fall in the US, is effective at boosting curcuminoid levels in the body at a “considerably smaller dose” than standard curcumin.

NutraCast: Improving CBD bioavailability with SmartSorb delivery technology

18-Mar-2022 By Danielle Masterson

Regulation of CBD, or lack thereof, is one challenge that the CBD industry faces. Another is bioavailability, which is impacted by quality, delivery method, and pharmacokinetics.

Cymbiotika launches UK e-commerce store for its natural supplements

16-Mar-2022 By Kavitha Sivasubramaniam

US nutritional supplement brand Cymbiotika has launched an e-commerce store in the UK for its range of natural supplements which aim to boost consumers’ vitality and longevity.

Krill oil-based delivery system improves absorption and benefits of ginger extract

21-Dec-2021 By Stephen Daniells

The oral availability of ginger extracts may be boosted by using a krill oil-based self-emulsifying drug delivery system (SEDDS), says a new study from Japan.

Low dose turmeric supplement offers 24-fold increased bioavailability, study says

29-Apr-2021 By Nicola Gordon-Seymour

The bioavailability of the curcuminoids in a low dose turmeric supplement were shown to be 24-times greater than a standard turmeric extract in a new randomised crossover study in France.

Caliper says university study backs bioavailability of its CBD formulations

10-Feb-2021 By Danielle Masterson

The study marks the first time humans were included in a peer-reviewed investigation of commercially available CBD product pharmacokinetics. Previous CBD studies have generally based their claims on animal model studies.

NutraVideo: Hemp Synergistics and SDC Nutrition announce collaboration

08-Dec-2020 By Danielle Masterson

Hemp Synergistics, a biotech company dedicated to making intelligent hemp products, recently announced that its broad-spectrum hemp oil will be used by global supplement manufacturer SDC Nutrition.

Church & Dwight agrees to drop gummy absorption claim, but says NAD process was unfair

27-Aug-2020 By Hank Schultz

Church & Dwight has lost an appeal and now has agreed to stop using a ‘clinically proven absortion’ claim on vitafusion brand of gummy vitamins.

‘Ground-breaking research’: Micromicellar formulation boosts carotenoid bioavailability in RCT

19-Aug-2020 By Stephen Daniells

Using a micromicellar formulation of lutein, zeaxanthin, and meso-zeaxanthin led to significantly higher increases in serum levels of the carotenoids, compared to other formulations, says a new study from Ireland.

Naturex’s Turmipure Gold to enter US food and beverage market following GRAS status

21-Jan-2020 By Danielle Masterson

Naturex, a plant extraction and ingredient developer, has obtained self-affirmed GRAS (Generally Recognized as Safe) designation for its turmeric extract, Turmipure Gold.

Bioavailability battle: Natural ingredients for functional foods in demand In APAC but challenges remain

02-Jan-2020 By Tingmin Koe

International ingredient firm Wacker says that the use of natural ingredients, such as curcumin and hydroxytyrosol in functional food is gaining steam in Asia, but there is a need to address issues such as low bioavailability.

News in brief

Micelle specialist issues updated financials detailing losses

09-Dec-2019 By Hank Schultz

A company based on a micellular delivery technology called Nurish.me has issued updated financial statements that have been signed off on by a third party auditor.

Quicksilver releases new enhanced CBD products

29-Oct-2019 By Hank Schultz

Colorado-based Quicksilver Scientific has joined the CBD bioavailability game with a new product line featuring the company’s proprietary liposomal delivery system.

Enough data backs benefits of timed nutrient delivery to support call for more research, study finds

06-Sep-2019 By Hank Schultz

Specific timing of nutrient delivery can have sports nutrition benefits, but the research is very much still in its infancy and as yet does not support much in the way of definitive recommendations, according to a new review.

Editor's Spotlight

Are ‘bioactive gels’ the future of multivitamins? Healthycell thinks so

15-May-2019 By Adi Menayang

Supplement company Healthycell is betting on a specialized gel format, served in single-serve sachets, to bring consumers what founder and CEO Douglas Giampapa argues is ‘maximum bioavailability’ of nutrients.

NutraIngredients Omega-3 Summit

WATCH: Absorption excellence — why customisation is key to boosting omega-3 bioavailabilty

06-Mar-2019 By Gary Scattergood

Customisation of fish and krill oil via delivery system technology is key to maximising the absorption qualities of omega-3, with three recent trials underlining its significance.

Plasma-treated whey increased circulating essential amino acids in blood, more so than conventional whey

26-Feb-2019 By Adi Menayang

Results from a new clinical trial suggest that participants who ingested a whey protein treated with atmospheric plasma had more circulating essential amino acids in the blood, hinting at improved muscle protein synthesis.

Pharmavite-backed study makes the case for new method to increase bioavailability of omega-3

15-Jan-2019 By Adi Menayang

Omega-3 fats delivered using a proprietary self-micro-emulsifying system may be more bioavailable to the human body than the standard ethyl ester formulation, according to a new study funded by Pharmavite.

These start-ups want to increase the bioavailability, efficacy of sports nutrition ingredients

30-Nov-2018 By Adi Menayang

We caught up with two start-ups, Plasma Nutrition and Tamarack Biotics, to learn more about the market and regulatory status of their novel processes and ingredients at the SupplySide West 2018 Expo.

Multivitamin chewing gum? Penn State research backs format's potential for vitamin delivery

11-Oct-2018 By Adi Menayang

Researchers from The Pennsylvania State University found that plasma concentrations of some vitamins increased after chewing gum fortified with these nutrients.

Manufacturer study adds evidence supporting more bioavailable form of arginine

11-Jul-2018 By Adi Menayang

Inositol-stabilized arginine is more bioavailable than arginine hydrochloride (HCL), according to new research by sports nutrition ingredient specialist Nutrition 21.

Next dimension of personalized nutrition? Startup Baze pushes into US dietary supplement market

25-Jun-2018 By Mary Ellen Shoup

Baze, an at-home blood testing kit that measures an individual’s micronutrient levels to determine a set of personalized monthly supplements, has completed a soft launch in the US aiming to introduce consumers to the “next level of dietary supplementation,”...

‘Plasma protein’ start-up adds new study to back its claims for better absorption than ‘normal’ whey

15-Jun-2018 By Adi Menayang

Blood analysis of participants who ingested either ‘plasma-blasted’ whey protein or standard hydrolyzed whey protein isolate suggests that the former is more bioavailable.

Battle of the omega-3 forms: Triglycerides, ethyl esters, or phospholipids?

21-Feb-2013 By Stephen DANIELLS

As the number of omega-3 sources in the market increases, including fish, krill, squid, algae, and plant, suppliers are increasingly using the omega-3 form to differentiate their products. But where does the science currently stand, which questions remain,...